human heart tissue were subjected to SDS PAGE followed by western blot with FNab02283(DDAH2 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human colon cancer using FNab02283(DDAH2 antibody) at dilution of 1:50
Immunofluorescence analysis of HeLa cells using FNab02283(DDAH2 antibody) at dilution of 1:50
Background
This gene encodes a dimethylarginine dimethylaminohydrolase. The encoded enzyme functions in nitric oxide generation by regulating the cellular concentrations of methylarginines, which in turn inhibit nitric oxide synthase activity. The protein may be localized to the mitochondria. Alternative splicing resulting in multiple transcript variants.